| Stem cell transcriptome profiling via massive-scale mRNA sequencing N Cloonan, ARR Forrest, G Kolle, B Gardiner, GJ Faulkner, MK Brown, ... Nature methods 5 (7), 613-619, 2008 | 1273 | 2008 |
| Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation ME Dinger, PP Amaral, TR Mercer, KC Pang, SJ Bruce, BB Gardiner, ... Genome research 18 (9), 1433-1445, 2008 | 844 | 2008 |
| Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF AC Parkins, AH Sharpe, SH Orkin Nature 375 (6529), 318-322, 1995 | 745 | 1995 |
| An essential role in liver development for transcription factor XBP-1 AM Reimold, A Etkin, I Clauss, A Perkins, DS Friend, J Zhang, HF Horton, ... Genes & development 14 (2), 152-157, 2000 | 590 | 2000 |
| Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells M Crossley, E Whitelaw, A Perkins, G Williams, Y Fujiwara, SH Orkin Molecular and Cellular Biology 16 (4), 1695-1705, 1996 | 283 | 1996 |
| A global role for EKLF in definitive and primitive erythropoiesis D Hodge, E Coghill, J Keys, T Maguire, B Hartmann, A McDowall, ... Blood 107 (8), 3359-3370, 2006 | 258 | 2006 |
| SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis S Ganiatsas, L Kwee, Y Fujiwara, A Perkins, T Ikeda, MA Labow, LI Zon Proceedings of the National Academy of Sciences 95 (12), 6881-6886, 1998 | 247 | 1998 |
| Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I S Verstovsek, RA Mesa, J Gotlib, RS Levy, V Gupta, JF DiPersio, ... haematologica 100 (4), 479, 2015 | 224 | 2015 |
| A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells MR Tallack, T Whitington, WS Yuen, EN Wainwright, JR Keys, ... Genome research 20 (8), 1052-1063, 2010 | 223 | 2010 |
| Complex architecture and regulated expression of the Sox2ot locus during vertebrate development PP Amaral, C Neyt, SJ Wilkins, ME Askarian-Amiri, SM Sunkin, ... Rna 15 (11), 2013-2027, 2009 | 216 | 2009 |
| High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22 M Gulhane, L Murray, R Lourie, H Tong, YH Sheng, R Wang, A Kang, ... Scientific reports 6 (1), 1-17, 2016 | 213 | 2016 |
| Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates KS Kassahn, VT Dang, SJ Wilkins, AC Perkins, MA Ragan Genome research 19 (8), 1404-1418, 2009 | 211 | 2009 |
| Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. MW Kieran, AC Perkins, SH Orkin, LI Zon Proceedings of the National Academy of Sciences 93 (17), 9126-9131, 1996 | 211 | 1996 |
| Targeted Disruption of the Basic Krüppel-Like Factor Gene (Klf3) Reveals a Role in Adipogenesis N Sue, BHA Jack, SA Eaton, RCM Pearson, APW Funnell, J Turner, ... Molecular and cellular biology 28 (12), 3967-3978, 2008 | 206 | 2008 |
| Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. A Perkins, K Kongsuwan, J Visvader, JM Adams, S Cory Proceedings of the National Academy of Sciences 87 (21), 8398-8402, 1990 | 203 | 1990 |
| A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis AM Vannucchi, HM Kantarjian, JJ Kiladjian, J Gotlib, F Cervantes, ... haematologica 100 (9), 1139, 2015 | 198 | 2015 |
| Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial RA Mesa, AM Vannucchi, A Mead, M Egyed, A Szoke, A Suvorov, ... The Lancet Haematology 4 (5), e225-e236, 2017 | 181 | 2017 |
| Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF. AC Perkins, KM Gaensler, SH Orkin Proceedings of the National Academy of Sciences 93 (22), 12267-12271, 1996 | 174 | 1996 |
| Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor P Papathanasiou, AC Perkins, BS Cobb, R Ferrini, R Sridharan, ... Immunity 19 (1), 131-144, 2003 | 157 | 2003 |
| Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease H Lu, MCR Galeano, E Ott, G Kaeslin, PJ Kausalya, C Kramer, ... Nature genetics 49 (7), 1025-1034, 2017 | 139 | 2017 |
Stuart OrkinПотвърден имейл адрес: dfci.harvard.edu
