| IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ... Nature 552 (7683), 110-115, 2017 | 479 | 2017 |
| The translational landscape of the human heart S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ... Cell 178 (1), 242-260. e29, 2019 | 404 | 2019 |
| Extensive localization of long noncoding RNAs to the cytosol and mono-and polyribosomal complexes S van Heesch, M van Iterson, J Jacobi, S Boymans, PB Essers, ... Genome biology 15 (1), 1-12, 2014 | 379 | 2014 |
| Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors P Kemmeren, K Sameith, LAL Van De Pasch, JJ Benschop, TL Lenstra, ... Cell 157 (3), 740-752, 2014 | 315 | 2014 |
| Titin-truncating variants affect heart function in disease cohorts and the general population S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ... Nature genetics 49 (1), 46-53, 2017 | 273 | 2017 |
| The specificity and topology of chromatin interaction pathways in yeast TL Lenstra, JJ Benschop, TS Kim, JM Schulze, NACH Brabers, ... Molecular cell 42 (4), 536-549, 2011 | 252 | 2011 |
| Distribution and functional impact of DNA copy number variation in the rat V Guryev, K Saar, T Adamovic, M Verheul, SAAC Van Heesch, S Cook, ... Nature genetics 40 (5), 538-545, 2008 | 231 | 2008 |
| Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain R van Nuland, FMA van Schaik, M Simonis, S van Heesch, E Cuppen, ... Epigenetics & chromatin 6, 1-12, 2013 | 159 | 2013 |
| The PLETHORA gene regulatory network guides growth and cell differentiation in Arabidopsis roots L Santuari, GF Sanchez-Perez, M Luijten, B Rutjens, I Terpstra, L Berke, ... The Plant Cell 28 (12), 2937-2951, 2016 | 143 | 2016 |
| Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis TY Low, S van Heesch, H van den Toorn, P Giansanti, A Cristobal, ... Cell reports 5 (5), 1469-1478, 2013 | 125 | 2013 |
| Standardized annotation of translated open reading frames JM Mudge, J Ruiz-Orera, JR Prensner, MA Brunet, F Calvet, I Jungreis, ... Nature biotechnology 40 (7), 994-999, 2022 | 90* | 2022 |
| Widespread translational control of fibrosis in the human heart by RNA-binding proteins S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ... Circulation 140 (11), 937-951, 2019 | 87 | 2019 |
| Translational regulation shapes the molecular landscape of complex disease phenotypes S Schafer, E Adami, M Heinig, KEC Rodrigues, F Kreuchwig, J Silhavy, ... Nature communications 6 (1), 7200, 2015 | 84 | 2015 |
| Large-scale identification of coregulated enhancer networks in the adult human brain MW Vermunt, P Reinink, J Korving, E de Bruijn, PM Creyghton, O Basak, ... Cell reports 9 (2), 767-779, 2014 | 74 | 2014 |
| Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations A Fomin, A Gärtner, L Cyganek, M Tiburcy, I Tuleta, L Wellers, L Folsche, ... Science translational medicine 13 (618), eabd3079, 2021 | 52 | 2021 |
| Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing S van Heesch, WP Kloosterman, N Lansu, FP Ruzius, E Levandowsky, ... BMC genomics 14 (1), 1-11, 2013 | 50 | 2013 |
| Systematic biases in DNA copy number originate from isolation procedures S van Heesch, M Mokry, V Boskova, W Junker, R Mehon, P Toonen, ... Genome biology 14 (4), 1-9, 2013 | 45 | 2013 |
| Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency R van Boxtel, RV Kuiper, PW Toonen, S van Heesch, R Hermsen, ... The American journal of pathology 179 (4), 1616-1622, 2011 | 42 | 2011 |
| Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel M Simonis, SS Atanur, S Linsen, V Guryev, FP Ruzius, L Game, N Lansu, ... Genome biology 13 (4), 1-17, 2012 | 37 | 2012 |
| Genomic and functional overlap between somatic and germline chromosomal rearrangements S van Heesch, M Simonis, MJ van Roosmalen, V Pillalamarri, H Brand, ... Cell reports 9 (6), 2001-2010, 2014 | 29 | 2014 |
Edwin CuppenHoogleraar Humane GeneticaVerified email at umcutrecht.nl
