Sebastiaan van Heesch
Sebastiaan van Heesch
Group Leader at Princess Máxima Center for Pediatric Oncology
Verified email at - Homepage
Cited by
Cited by
IL-11 is a crucial determinant of cardiovascular fibrosis
S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ...
Nature 552 (7683), 110-115, 2017
The translational landscape of the human heart
S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ...
Cell 178 (1), 242-260. e29, 2019
Extensive localization of long noncoding RNAs to the cytosol and mono-and polyribosomal complexes
S van Heesch, M van Iterson, J Jacobi, S Boymans, PB Essers, ...
Genome biology 15 (1), 1-12, 2014
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors
P Kemmeren, K Sameith, LAL Van De Pasch, JJ Benschop, TL Lenstra, ...
Cell 157 (3), 740-752, 2014
Titin-truncating variants affect heart function in disease cohorts and the general population
S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ...
Nature genetics 49 (1), 46-53, 2017
The specificity and topology of chromatin interaction pathways in yeast
TL Lenstra, JJ Benschop, TS Kim, JM Schulze, NACH Brabers, ...
Molecular cell 42 (4), 536-549, 2011
Distribution and functional impact of DNA copy number variation in the rat
V Guryev, K Saar, T Adamovic, M Verheul, SAAC Van Heesch, S Cook, ...
Nature genetics 40 (5), 538-545, 2008
Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
R van Nuland, FMA van Schaik, M Simonis, S van Heesch, E Cuppen, ...
Epigenetics & chromatin 6, 1-12, 2013
The PLETHORA gene regulatory network guides growth and cell differentiation in Arabidopsis roots
L Santuari, GF Sanchez-Perez, M Luijten, B Rutjens, I Terpstra, L Berke, ...
The Plant Cell 28 (12), 2937-2951, 2016
Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis
TY Low, S van Heesch, H van den Toorn, P Giansanti, A Cristobal, ...
Cell reports 5 (5), 1469-1478, 2013
Standardized annotation of translated open reading frames
JM Mudge, J Ruiz-Orera, JR Prensner, MA Brunet, F Calvet, I Jungreis, ...
Nature biotechnology 40 (7), 994-999, 2022
Widespread translational control of fibrosis in the human heart by RNA-binding proteins
S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ...
Circulation 140 (11), 937-951, 2019
Translational regulation shapes the molecular landscape of complex disease phenotypes
S Schafer, E Adami, M Heinig, KEC Rodrigues, F Kreuchwig, J Silhavy, ...
Nature communications 6 (1), 7200, 2015
Large-scale identification of coregulated enhancer networks in the adult human brain
MW Vermunt, P Reinink, J Korving, E de Bruijn, PM Creyghton, O Basak, ...
Cell reports 9 (2), 767-779, 2014
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations
A Fomin, A Gärtner, L Cyganek, M Tiburcy, I Tuleta, L Wellers, L Folsche, ...
Science translational medicine 13 (618), eabd3079, 2021
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing
S van Heesch, WP Kloosterman, N Lansu, FP Ruzius, E Levandowsky, ...
BMC genomics 14 (1), 1-11, 2013
Systematic biases in DNA copy number originate from isolation procedures
S van Heesch, M Mokry, V Boskova, W Junker, R Mehon, P Toonen, ...
Genome biology 14 (4), 1-9, 2013
Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency
R van Boxtel, RV Kuiper, PW Toonen, S van Heesch, R Hermsen, ...
The American journal of pathology 179 (4), 1616-1622, 2011
Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel
M Simonis, SS Atanur, S Linsen, V Guryev, FP Ruzius, L Game, N Lansu, ...
Genome biology 13 (4), 1-17, 2012
Genomic and functional overlap between somatic and germline chromosomal rearrangements
S van Heesch, M Simonis, MJ van Roosmalen, V Pillalamarri, H Brand, ...
Cell reports 9 (6), 2001-2010, 2014
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