Jason M. Kinchen
Jason M. Kinchen
Owlstone Medical, Inc
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Pannexin 1 channels mediate ‘find-me’signal release and membrane permeability during apoptosis
FB Chekeni, MR Elliott, JK Sandilos, SF Walk, JM Kinchen, ...
Nature 467 (7317), 863-867, 2010
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
TL Gumienny, E Brugnera, AC Tosello-Trampont, JM Kinchen, LB Haney, ...
Cell 107 (1), 27-41, 2001
Phagosome maturation: going through the acid test
JM Kinchen, KS Ravichandran
Nature reviews Molecular cell biology 9 (10), 781-795, 2008
Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans
JM Kinchen, J Cabello, D Klingele, K Wong, R Feichtinger, H Schnabel, ...
Nature 434 (7029), 93-99, 2005
A pathway for phagosome maturation during engulfment of apoptotic cells
JM Kinchen, K Doukoumetzidis, J Almendinger, L Stergiou, ...
Nature cell biology 10 (5), 556-566, 2008
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
JM Kinchen, KS Ravichandran
Nature 464 (7289), 778-782, 2010
Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion
AE Hochreiter-Hufford, CS Lee, JM Kinchen, JD Sokolowski, ...
Nature 497 (7448), 263-267, 2013
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
CM Grimsley, JM Kinchen, AC Tosello-Trampont, E Brugnera, LB Haney, ...
Journal of Biological Chemistry 279 (7), 6087-6097, 2004
Unexpected link between an antibiotic, pannexin channels and apoptosis
IKH Poon, YH Chiu, AJ Armstrong, JM Kinchen, IJ Juncadella, DA Bayliss, ...
Nature 507 (7492), 329-334, 2014
Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO
C deBakker, L Haney, J Kinchen, C Grimsley, M Lu, D Klingele, PK Hsu, ...
Current biology 14 (24), 2208-2216, 2004
Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein
D Park, CZ Han, MR Elliott, JM Kinchen, PC Trampont, S Das, S Collins, ...
Nature 477 (7363), 220-224, 2011
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation
CZ Han, IJ Juncadella, JM Kinchen, MW Buckley, AL Klibanov, K Dryden, ...
Nature 539 (7630), 570-574, 2016
Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair
S Zhang, S Weinberg, M DeBerge, A Gainullina, M Schipma, JM Kinchen, ...
Cell metabolism 29 (2), 443-456. e5, 2019
Defining the independence of the liver circadian clock
KB Koronowski, K Kinouchi, PS Welz, JG Smith, VM Zinna, J Shi, ...
Cell 177 (6), 1448-1462. e14, 2019
Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo
MR Elliott, S Zheng, D Park, RI Woodson, MA Reardon, IJ Juncadella, ...
Nature 467 (7313), 333-337, 2010
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
M Lu, JM Kinchen, KL Rossman, C Grimsley, C DeBakker, E Brugnera, ...
Nature structural & molecular biology 11 (8), 756-762, 2004
A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs
M Lu, JM Kinchen, KL Rossman, C Grimsley, M Hall, J Sondek, ...
Current Biology 15 (4), 371-377, 2005
Journey to the grave: signaling events regulating removal of apoptotic cells
JM Kinchen, KS Ravichandran
Journal of cell science 120 (13), 2143-2149, 2007
Metabolomic and genome‐wide association studies reveal potential endogenous biomarkers for OATP1B1
SW Yee, MM Giacomini, CH Hsueh, D Weitz, X Liang, S Goswami, ...
Clinical Pharmacology & Therapeutics 100 (5), 524-536, 2016
An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response
MA Gronski, JM Kinchen, IJ Juncadella, NC Franc, KS Ravichandran
Cell Death & Differentiation 16 (10), 1323-1331, 2009
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