| Transamidation of primary amides with amines using hydroxylamine hydrochloride as an inorganic catalyst CL Allen, BN Atkinson, JMJ Williams Angewandte Chemie International Edition 6 (51), 1383-1386, 2012 | 243 | 2012 |
| Transamidation of primary amides with amines catalyzed by zirconocene dichloride BN Atkinson, AR Chhatwal, HV Lomax, JW Walton, JMJ Williams Chemical communications 48 (95), 11626-11628, 2012 | 100 | 2012 |
| Dimethylsulfoxide as an N-Methylation Reagent for Amines and Aromatic Nitro Compounds BN Atkinson, JMJ Williams ChemCatChem 6 (7), 1860-1862, 2014 | 40 | 2014 |
| Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen BN Atkinson, D Steadman, Y Zhao, J Sipthorp, L Vecchia, RR Ruza, ... MedChemComm 10 (8), 1361-1369, 2019 | 28 | 2019 |
| Carboxylesterase notum is a druggable target to modulate Wnt signaling ED Bayle, F Svensson, BN Atkinson, D Steadman, NJ Willis, ... Journal of medicinal chemistry 64 (8), 4289-4311, 2021 | 25 | 2021 |
| Scandium triflate catalyzed ester synthesis using primary amides BN Atkinson, JMJ Williams Tetrahedron letters 55 (50), 6935-6938, 2014 | 24 | 2014 |
| Scaffold-hopping identifies furano [2, 3-d] pyrimidine amides as potent Notum inhibitors BN Atkinson, D Steadman, W Mahy, Y Zhao, J Sipthorp, ED Bayle, ... Bioorganic & Medicinal Chemistry Letters 30 (3), 126751, 2020 | 15 | 2020 |
| Screening of a custom-designed acid fragment library identifies 1-phenylpyrroles and 1-phenylpyrrolidines as inhibitors of Notum carboxylesterase activity W Mahy, M Patel, D Steadman, HL Woodward, BN Atkinson, F Svensson, ... Journal of medicinal chemistry 63 (17), 9464-9483, 2020 | 14 | 2020 |
| Ruthenium‐Catalyzed Remote Electronic Activation of Aromatic C F Bonds AJA Watson, BN Atkinson, AC Maxwell, JMJ Williams Advanced Synthesis & Catalysis 355 (4), 734-740, 2013 | 14 | 2013 |
| An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1, 2-benziodoxol-3-one as a superior electrophilic chlorinating agent NJ Willis, ED Bayle, G Papageorgiou, D Steadman, BN Atkinson, W Mahy, ... Beilstein Journal of Organic Chemistry 15 (1), 2790-2797, 2019 | 11 | 2019 |
| Virtual screening directly identifies new fragment-sized inhibitors of carboxylesterase Notum with nanomolar activity D Steadman, BN Atkinson, Y Zhao, NJ Willis, S Frew, A Monaghan, ... Journal of Medicinal Chemistry 65 (1), 562-578, 2021 | 10 | 2021 |
| Cyclohexyl amide derivatives as CRF receptor antagonists B Atkinson, D Beattie, AJ Culshaw, J Dale, NJ Devereux, J McKenna US Patent App. 13/017,399, 2011 | 10 | 2011 |
| Design of a Potent, selective, and brain-penetrant inhibitor of Wnt-deactivating enzyme notum by optimization of a crystallographic fragment hit NJ Willis, W Mahy, J Sipthorp, Y Zhao, HL Woodward, BN Atkinson, ... Journal of medicinal chemistry 65 (10), 7212-7230, 2022 | 9 | 2022 |
| Catalytic Amide Bond Forming Methods BN Atkinson, AR Chhatwal, JMJ Williams | 9 | 2016 |
| Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives BN Atkinson, HL Woodward, J Sipthorp, PV Fish Organic & Biomolecular Chemistry 15 (46), 9794-9799, 2017 | 5 | 2017 |
| Structural analysis and development of Notum fragment screening hits Y Zhao, W Mahy, NJ Willis, HL Woodward, D Steadman, ED Bayle, ... ACS Chemical Neuroscience 13 (13), 2060-2077, 2022 | 4 | 2022 |
| Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity BN Atkinson, NJ Willis, Y Zhao, C Patel, S Frew, K Costelloe, L Magno, ... European Journal of Medicinal Chemistry 251, 115132, 2023 | 3 | 2023 |
| Large-scale synthesis of Notum inhibitor 1-(2, 4-dichloro-3-(trifluoromethyl)-phenyl)-1 H-1, 2, 3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step BN Atkinson, NJ Willis, J Smith, R Gill, J Ali, Z Xu, PS Lai, PV Fish RSC advances 12 (41), 26497-26503, 2022 | 3 | 2022 |
| Controlling engineered P2X receptors with light BN Atkinson, V Chudasama, LE Browne Purinergic Signaling: Methods and Protocols, 301-309, 2020 | 1 | 2020 |
| Metal Catalysed Acyl Transfer Reactions of Amides BN Atkinson University of Bath, 2014 | 1 | 2014 |
