| Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity B Chetan, M Bunha, M Jagrat, BN Sinha, P Saiko, G Graser, T Szekeres, ... Bioorganic & medicinal chemistry letters 20, 3906-3010, 2010 | 76 | 2010 |
| DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis MR Bhonde, ML Hanski, J Budczies, M Cao, B Gillissen, D Moorthy, ... Journal of biological chemistry 281 (13), 8675-8685, 2006 | 54 | 2006 |
| The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein MR Bhonde, ML Hanski, R Magrini, D Moorthy, A Müller, EA Sausville, ... Oncogene 24 (1), 148-156, 2005 | 35 | 2005 |
| Synthesis of 2-substituted 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures G Panchapakesan, V Dhayalan, ND Moorthy, N Saranya, ... Steroids 76 (13), 1491-1504, 2011 | 23 | 2011 |
| Synthesis and biological evaluation of calothrixins B and their deoxygenated analogs BM Ramalingam, ND Moorthy, SR Chowdhury, T Mageshwaran, ... J. Med. Chem 61, 1285-1315, 2018 | 22 | 2018 |
| Targeted fusion proteins for cancer therapy K Maithal, DM Nachiappan, R Mukherjee US Patent App. 12/093,697, 2010 | 15 | 2010 |
| Divergent Synthesis and Evaluation of the in vitro Cytotoxicity Profiles of 3, 4‐Ethylenedioxythiophenyl‐2‐propen‐1‐one Analogues J Karunakaran, N Dhatchana Moorthy, SR Chowdhury, S Iqbal, ... ChemMedChem 14 (15), 1418-1430, 2019 | 7 | 2019 |
| Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues AKM Bose Muthu Ramalingam, Nachiappan Dhatchana Moorthy, Somenath Roy ... Journal of Medicinal Chemistry, 2018 | 7 | 2018 |
| Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage N Dhatchana Moorthy, B Muthu Ramalingam, S Iqbal, ... PLoS One 13 (9), e0202903, 2018 | 6 | 2018 |
| Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage ND Moorthy, BM Ramalingam, S Iqbal, AK Mohanakrishnan, ... Plos one 13 (9), 2018 | 6 | 2018 |
| Synthesis of Thia-Analogues of Calothrixin B Involving FeCl3-Mediated Domino Reaction BM Ramalingam, ND Moorthy, E Vellaichamy, AK Mohanakrishnan Synlett 28 (01), 133-137, 2017 | 5 | 2017 |
| Functional characterization of Candida albicans Hos2 histone deacetylase G Karthikeyan, M Paul-Satyaseela, ND Moorthy, R Gopalaswamy, ... F1000Research 2, 238, 2013 | 5 | 2013 |
| Synthesis and in vitro cytotoxicity of 2-substituted 17-methylene/17-ß-methyl estratrienes G Panchapakesan, R Sureshbabu, D Moorthy, AK Mohanakrishnan Indian journal of chemistry 52, 109-121, 2013 | | 2013 |
| Targeting solid tumors with a distinct synthetic class selective histone deacetylase inhibitor: OCID 4681-S-01 AM Roy, S Nidhyanandan, NK Reddy, M John, S Bhamre, D Jayaram, ... 9th International symposium on targeted anticancer therapies 22, iii31–iii34, 2011 | | 2011 |
| Synthesis of 2-substitued 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures P G, D V, D Moorthy N, S N, M AK Steroids 76 (13), 1491-1504, 2011 | | 2011 |
| CHARACTERIZATION OF OCID 4681-S-01, A NOVEL CLASS-SELECTIVE HDAC INHIBITOR FOR TARGETED THERAPY OF CANCER S Narayanan, N Nithyanandan, D Moorthy, F Ahamed, N Surendran, ... ANNALS OF ONCOLOGY 21, 35-35, 2010 | | 2010 |
| Pharmacological characterization of OCID 4681-S-01, a novel class-selective HDAC inhibitor for targeted therapy of cancer S Narayanan, N Nithyanandan, D Moorthy, F Ahamed, N Surendran, ... 8th International symposium on targeted anticancer therapies 21, ii34–ii38, 2010 | | 2010 |
| p53-unabhängige Apoptose: Charakterisierung der Irinotecan-induzierten mitotischen Katastrophe in Kolonkarzinomzellen M Bhonde, ML Hanski, J Budczies, M Cao, B Gillissen, D Moorthy, ... Zeitschrift für Gastroenterologie 44 (08), P300, 2006 | | 2006 |
| Targeted fusion proteins for cancer therapy RM Kapil Maithal, Dhatchana Moorthy WO Patent 2007/057,922, 2006 | | 2006 |
| Mikroarray-Analyse der p53-abhängigen und p53-unabhängigen transkriptionellen Antwort von Kolonkarzinomzellen auf DNA-Schädigung durch Irinotecan MR Bhonde, D Moorthy, ML Hanski, R Magrini, M Notter, B Mann, ... Zeitschrift für Gastroenterologie 41 (08), P240, 2003 | | 2003 |
kannan mohanakrishnanProfessor of Organic Chemistry, University of MadrasПотвърден имейл адрес: unom.ac.in
