Следене
Daniel G. Isom
Daniel G. Isom
University of Miami School of Medicine
Потвърден имейл адрес: miami.edu - Начална страница
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Позовавания
Позовавания
Година
Large shifts in pKa values of lysine residues buried inside a protein
DG Isom, CA Castañeda, BR Cannon, B García-Moreno E
Proceedings of the National Academy of Sciences 108 (13), 5260-5265, 2011
4952011
Charges in the hydrophobic interior of proteins
DG Isom, CA Castañeda, BR Cannon, PD Velu, B García-Moreno E
Proceedings of the National Academy of Sciences 107 (37), 16096-16100, 2010
2562010
High tolerance for ionizable residues in the hydrophobic interior of proteins
DG Isom, BR Cannon, CA Castañeda, A Robinson, B García-Moreno E
Proceedings of the National Academy of Sciences 105 (46), 17784-17788, 2008
1652008
The pKa values of acidic and basic residues buried at the same internal location in a protein are governed by different factors
MJ Harms, CA Castañeda, JL Schlessman, GR Sue, DG Isom, ...
Journal of molecular biology 389 (1), 34-47, 2009
1572009
Local secondary structure content predicts folding rates for simple, two-state proteins
H Gong, DG Isom, R Srinivasan, GD Rose
Journal of molecular biology 327 (5), 1149-1154, 2003
1442003
One year of SARS-CoV-2: How much has the virus changed?
S Vilar, DG Isom
Biology 10 (2), 91, 2021
1262021
Protons as second messenger regulators of G protein signaling
DG Isom, V Sridharan, R Baker, ST Clement, DM Smalley, HG Dohlman
Molecular cell 51 (4), 531-538, 2013
822013
Mutations in ATP1A1 cause dominant Charcot-Marie-Tooth type 2
P Lassuthova, AP Rebelo, G Ravenscroft, PJ Lamont, MR Davis, ...
The American Journal of Human Genetics 102 (3), 505-514, 2018
782018
Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination
R Baker, EM Wilkerson, K Sumita, DG Isom, AT Sasaki, HG Dohlman, ...
Journal of Biological Chemistry 288 (52), 36856-36862, 2013
742013
Hydration of the folding transition state ensemble of a protein
L Brun, DG Isom, P Velu, B García-Moreno, CA Royer
Biochemistry 45 (11), 3473-3480, 2006
582006
DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery
NJ Kapolka, GJ Taghon, JB Rowe, WM Morgan, JF Enten, NA Lambert, ...
Proceedings of the National Academy of Sciences 117 (23), 13117-13126, 2020
522020
Predictable cholesterol binding sites in GPCRs lack consensus motifs
GJ Taghon, JB Rowe, NJ Kapolka, DG Isom
Structure 29 (5), 499-506. e3, 2021
462021
Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activation
DG Isom, HG Dohlman
Proceedings of the National Academy of Sciences 112 (18), 5702-5707, 2015
452015
The evolution and mechanism of GPCR proton sensing
JB Rowe, NJ Kapolka, GJ Taghon, WM Morgan, DG Isom
Journal of Biological Chemistry 296, 2021
422021
V i-value analysis: a pressure-based method for mapping the folding transition state ensemble of proteins
L Mitra, K Hata, R Kono, A Maeno, D Isom, JB Rouget, R Winter, ...
Journal of the American Chemical Society 129 (46), 14108-14109, 2007
392007
Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity
DG Isom, E Vardy, TG Oas, HW Hellinga
Proceedings of the National Academy of Sciences 107 (11), 4908-4913, 2010
362010
A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity
DG Isom, PR Marguet, TG Oas, HW Hellinga
Proteins: Structure, Function, and Bioinformatics 79 (4), 1034-1047, 2011
352011
Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast
DG Isom, SC Page, LB Collins, NJ Kapolka, GJ Taghon, HG Dohlman
Journal of Biological Chemistry 293 (7), 2318-2329, 2018
312018
Amino acid metabolites that regulate G protein signaling during osmotic stress
JP Shellhammer, E Morin-Kensicki, JP Matson, G Yin, DG Isom, ...
PLoS Genetics 13 (5), e1006829, 2017
222017
HCAR3: an underexplored metabolite sensor
NJ Kapolka, DG Isom
Nature reviews. Drug discovery 19 (11), 745, 2020
202020
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Статии 1–20