Следене
Matthew R. Gazzara
Matthew R. Gazzara
PhD Student, Genomics and Computational Biology, University of Pennsylvania
Потвърден имейл адрес: pennmedicine.upenn.edu
Заглавие
Позовавания
Позовавания
Година
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ...
Cancer discovery 5 (12), 1282-1295, 2015
12032015
A new view of transcriptome complexity and regulation through the lens of local splicing variations
J Vaquero-Garcia, A Barrera, MR Gazzara, J Gonzalez-Vallinas, ...
elife 5, e11752, 2016
4152016
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19
M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ...
Leukemia 34 (4), 1202-1207, 2020
742020
Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation
NM Martinez, L Agosto, J Qiu, MJ Mallory, MR Gazzara, Y Barash, X Fu, ...
Genes & development 29 (19), 2054-2066, 2015
742015
Integrative deep models for alternative splicing
A Jha, MR Gazzara, Y Barash
Bioinformatics 33 (14), i274-i282, 2017
692017
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling
MJ Mallory, SJ Allon, J Qiu, MR Gazzara, I Tapescu, NM Martinez, XD Fu, ...
Proceedings of the National Academy of Sciences 112 (17), E2139-E2148, 2015
692015
Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing
MG Thompson, R Muñoz-Moreno, P Bhat, R Roytenberg, J Lindberg, ...
Nature communications 9 (1), 2407, 2018
652018
Aberrant splicing in B-cell acute lymphoblastic leukemia
KL Black, AS Naqvi, M Asnani, KE Hayer, SY Yang, E Gillespie, ...
Nucleic acids research 46 (21), 11357-11369, 2018
612018
Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes
MR Gazzara, MJ Mallory, R Roytenberg, JP Lindberg, A Jha, KW Lynch, ...
Genome research 27 (8), 1360-1370, 2017
472017
Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells
S Ajith, MR Gazzara, BS Cole, G Shankarling, NM Martinez, MJ Mallory, ...
RNA biology 13 (6), 569-581, 2016
472016
Enhanced integrated gradients: improving interpretability of deep learning models using splicing codes as a case study
A Jha, J K. Aicher, M R. Gazzara, D Singh, Y Barash
Genome biology 21, 1-22, 2020
452020
Mutator dynamics in sexual and asexual experimental populations of yeast
Y Raynes, MR Gazzara, PD Sniegowski
BMC evolutionary biology 11, 1-7, 2011
382011
RNA binding protein CELF2 regulates signal-induced alternative polyadenylation by competing with enhancers of the polyadenylation machinery
R Chatrikhi, MJ Mallory, MR Gazzara, LM Agosto, WS Zhu, AJ Litterman, ...
Cell reports 28 (11), 2795-2806. e3, 2019
342019
An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning
I Ehrmann, JH Crichton, MR Gazzara, K James, Y Liu, SN Grellscheid, ...
Elife 8, e39304, 2019
282019
Deep profiling and custom databases improve detection of proteoforms generated by alternative splicing
LM Agosto, MR Gazzara, CM Radens, S Sidoli, J Baeza, BA Garcia, ...
Genome research 29 (12), 2046-2055, 2019
272019
Contrasting dynamics of a mutator allele in asexual populations of differing size
Y Raynes, MR Gazzara, PD Sniegowski
Evolution 66 (7), 2329-2334, 2012
272012
A SLM2 feedback pathway controls cortical network activity and mouse behavior
I Ehrmann, MR Gazzara, V Pagliarini, C Dalgliesh, ...
Cell reports 17 (12), 3269-3280, 2016
232016
Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells
MJ Mallory, SP McClory, R Chatrikhi, MR Gazzara, RJ Ontiveros, ...
Nucleic acids research 48 (10), 5710-5719, 2020
222020
MAJIQ-SPEL: web-tool to interrogate classical and complex splicing variations from RNA-Seq data
CJ Green, MR Gazzara, Y Barash
Bioinformatics 34 (2), 300-302, 2018
212018
Analysis of scientific society honors reveals disparities
TT Le, DS Himmelstein, AA Hippen, MR Gazzara, CS Greene
Cell Systems 12 (9), 900-906. e5, 2021
19*2021
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