| Myocardial fatty acid metabolism in health and disease GD Lopaschuk, JR Ussher, CDL Folmes, JS Jaswal, WC Stanley Physiological Reviews 90 (1), 207-258, 2010 | 2333 | 2010 |
| Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ... Cell metabolism 7 (1), 45-56, 2008 | 2127 | 2008 |
| Cardiovascular Biology of the Incretin System JR Ussher, DJ Drucker Endocrine Reviews, 2012 | 651 | 2012 |
| Targeting fatty acid and carbohydrate oxidation-A novel therapeutic intervention in the ischemic and failing heart JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2011 | 469 | 2011 |
| Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ... Diabetes 59 (10), 2453-2464, 2010 | 401 | 2010 |
| Cardiovascular actions of incretin-based therapies JR Ussher, DJ Drucker Circulation research 114 (11), 1788-1803, 2014 | 377 | 2014 |
| The emerging role of metabolomics in the diagnosis and prognosis of cardiovascular disease JR Ussher, S Elmariah, RE Gerszten, JRB Dyck Journal of the American College of Cardiology 68 (25), 2850-2870, 2016 | 313 | 2016 |
| Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy L Zhang, JS Jaswal, JR Ussher, S Sankaralingam, C Wagg, M Zaugg, ... Circulation: Heart Failure 6 (5), 1039-1048, 2013 | 260 | 2013 |
| Gut microbiota metabolism of L-carnitine and cardiovascular risk JR Ussher, GD Lopaschuk, A Arduini Atherosclerosis 231 (2), 456-461, 2013 | 212 | 2013 |
| Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury JR Ussher, W Wang, M Gandhi, W Keung, V Samokhvalov, T Oka, ... Cardiovascular research 94 (2), 359-369, 2012 | 195 | 2012 |
| Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function R Basu, GY Oudit, X Wang, L Zhang, JR Ussher, GD Lopaschuk, Z Kassiri American Journal of Physiology-Heart and Circulatory Physiology 297 (6 …, 2009 | 189 | 2009 |
| Lipotoxicity in obesity and diabetes-related cardiac dysfunction I Zlobine, K Gopal, JR Ussher Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 167 | 2016 |
| Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation L Zhang, JR Ussher, T Oka, VJJ Cadete, C Wagg, GD Lopaschuk Cardiovascular research 89 (1), 148-156, 2011 | 150 | 2011 |
| Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ... Cardiovascular research 115 (11), 1606-1616, 2019 | 146 | 2019 |
| Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase JR Ussher, TR Koves, JS Jaswal, L Zhang, O Ilkayeva, JRB Dyck, ... Diabetes 58 (8), 1766-1775, 2009 | 146 | 2009 |
| Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice W Keung, JR Ussher, JS Jaswal, M Raubenheimer, VHM Lam, CS Wagg, ... Diabetes 62 (3), 711-720, 2013 | 144 | 2013 |
| Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection JR Ussher, LL Baggio, JE Campbell, EE Mulvihill, M Kim, MG Kabir, ... Molecular metabolism 3 (5), 507-517, 2014 | 130 | 2014 |
| Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ... Cardiovascular diabetology 18, 1-12, 2019 | 122 | 2019 |
| TCF1 links GIPR signaling to the control of beta cell function and survival JE Campbell, JR Ussher, EE Mulvihill, J Kolic, LL Baggio, X Cao, Y Liu, ... Nature medicine 22 (1), 84-90, 2016 | 122 | 2016 |
| Evolving concepts of myocardial energy metabolism: more than just fats and carbohydrates GD Lopaschuk, JR Ussher Circulation Research 119 (11), 1173-1176, 2016 | 121 | 2016 |
Gary LopaschukProfessor, Pediatrics, Universit of AlbertaVerified email at ualberta.ca
