| Computational methods in drug discovery G Sliwoski, S Kothiwale, J Meiler, EW Lowe Pharmacological reviews 66 (1), 334-395, 2014 | 2238 | 2014 |
| Protocols for molecular modeling with Rosetta3 and RosettaScripts BJ Bender, A Cisneros III, AM Duran, JA Finn, D Fu, AD Lokits, BK Mueller, ... Biochemistry 55 (34), 4748-4763, 2016 | 203 | 2016 |
| An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer AB Hanker, MR Brewer, JH Sheehan, JP Koch, GR Sliwoski, R Nagy, ... Cancer discovery 7 (6), 575-585, 2017 | 104* | 2017 |
| Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign G Sliwoski, J Mendenhall, J Meiler Journal of computer-aided molecular design 30, 209-217, 2016 | 47 | 2016 |
| Clozapine interaction with phosphatidyl inositol 3-kinase (PI3K)/insulin-signaling pathway in Caenorhabditis elegans R Karmacharya, GR Sliwoski, MY Lundy, RF Suckow, BM Cohen, ... Neuropsychopharmacology 34 (8), 1968-1978, 2009 | 42 | 2009 |
| Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6 A Brüser, A Zimmermann, BC Crews, G Sliwoski, J Meiler, GM König, ... Scientific Reports 7 (1), 2380, 2017 | 39 | 2017 |
| Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket X Pedragosa-Badia, GR Sliwoski, ED Nguyen, D Lindner, J Stichel, ... Journal of Biological Chemistry 289 (9), 5846-5859, 2014 | 38 | 2014 |
| PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors S Croessmann, JH Sheehan, K Lee, G Sliwoski, J He, R Nagy, D Riddle, ... Clinical Cancer Research 24 (6), 1426-1435, 2018 | 36 | 2018 |
| A Genome-Wide RNAi Screen in Caenorhabditis elegans Identifies the Nicotinic Acetylcholine Receptor Subunit ACR-7 as an Antipsychotic Drug Target T Saur, SE DeMarco, A Ortiz, GR Sliwoski, L Hao, X Wang, BM Cohen, ... PLoS genetics 9 (2), e1003313, 2013 | 32 | 2013 |
| Discovery and characterization of a selective activator of the G-protein activated inward-rectifying potassium (GIRK) channel E Days, K Kaufmann, I Romaine, C Niswender, M Lewis, T Utley, Y Du, ... | 21 | 2013 |
| Discovery of Small-Molecule Modulators of the Human Y4 Receptor G Sliwoski, M Schubert, J Stichel, D Weaver, AG Beck-Sickinger, J Meiler PLoS one 11 (6), e0157146, 2016 | 18 | 2016 |
| Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator M Schubert, J Stichel, Y Du, IR Tough, G Sliwoski, J Meiler, HM Cox, ... Journal of Medicinal Chemistry 60 (17), 7605-7612, 2017 | 17 | 2017 |
| The Relevance ofCaenorhabditis elegansGenetics for Understanding Human Psychiatric Disease X Wang, GR Sliwoski, EA Buttner Harvard Review of Psychiatry 19 (4), 210-218, 2011 | 12 | 2011 |
| PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection ZZ Tang, GR Sliwoski, G Chen, B Jin, WS Bush, B Li, JA Capra Genome biology 21, 1-25, 2020 | 11 | 2020 |
| BCL:: EMAS—enantioselective molecular asymmetry descriptor for 3D-QSAR G Sliwoski, EW Lowe Jr, M Butkiewicz, J Meiler Molecules 17 (8), 9971-9989, 2012 | 11 | 2012 |
| The impact of natural selection on the evolution and function of placentally expressed galectins ZA Ely, JM Moon, GR Sliwoski, AK Sangha, XX Shen, AL Labella, J Meiler, ... Genome Biology and Evolution 11 (9), 2574-2592, 2019 | 9 | 2019 |
| Mapping the Binding Sites of UDP and Prostaglandin E2 Glyceryl Ester in the Nucleotide Receptor P2Y6 A Zimmermann, O Vu, A Brüser, G Sliwoski, LJ Marnett, J Meiler, ... ChemMedChem 17 (7), e202100683, 2022 | 3 | 2022 |
| Abstract PD3-05: Co-occurring gain-of-function mutations in HER2 and HER3 cooperate to enhance HER2/HER3 binding, HER-dependent signaling, and breast cancer growth AB Hanker, JP Koch, D Ye, G Sliwoski, J Sheehan, LN Kinch, ... Cancer Research 79 (4_Supplement), PD3-05-PD3-05, 2019 | 3 | 2019 |
| The impact of natural selection on the evolution and function of placentally expressed galectins ZA Ely, JM Moon, GR Sliwoski, AK Sangha, XX Shen, AL Labella, J Meiler, ... bioRxiv, 505339, 2018 | 2 | 2018 |
| Computer Aided Drug Discovery Descriptor Improvement and Application to Obesity-related Therapeutics G Sliwoski | 1 | 2015 |
