| Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study T Baba, A Kikuchi, K Hirayama, Y Nishio, Y Hosokai, S Kanno, ... Brain 135 (1), 161-169, 2012 | 326 | 2012 |
| VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease E Miura, T Hasegawa, M Konno, M Suzuki, N Sugeno, N Fujikake, ... Neurobiology of disease 71, 1-13, 2014 | 211 | 2014 |
| Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death N Sugeno, A Takeda, T Hasegawa, M Kobayashi, A Kikuchi, F Mori, ... Journal of Biological Chemistry 283 (34), 23179-23188, 2008 | 191 | 2008 |
| The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein T Hasegawa, M Konno, T Baba, N Sugeno, A Kikuchi, M Kobayashi, ... PloS one 6 (12), e29460, 2011 | 171 | 2011 |
| Plasma membrane ion permeability induced by mutant α‐synuclein contributes to the degeneration of neural cells K Furukawa, M Matsuzaki‐Kobayashi, T Hasegawa, A Kikuchi, N Sugeno, ... Journal of neurochemistry 97 (4), 1071-1077, 2006 | 146 | 2006 |
| Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy M Konno, T Hasegawa, T Baba, E Miura, N Sugeno, A Kikuchi, FC Fiesel, ... Molecular neurodegeneration 7, 1-16, 2012 | 139 | 2012 |
| In vivo visualization of α-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission … A Kikuchi, A Takeda, N Okamura, M Tashiro, T Hasegawa, S Furumoto, ... Brain 133 (6), 1772-1778, 2010 | 138 | 2010 |
| In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET A Kikuchi, N Okamura, T Hasegawa, R Harada, S Watanuki, Y Funaki, ... Neurology 87 (22), 2309-2316, 2016 | 125 | 2016 |
| Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease T Baba, A Takeda, A Kikuchi, Y Nishio, Y Hosokai, K Hirayama, ... Movement Disorders 26 (4), 621-628, 2011 | 107 | 2011 |
| α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses N Sugeno, S Jäckel, A Voigt, Z Wassouf, J Schulze-Hentrich, PJ Kahle Scientific reports 6 (1), 36328, 2016 | 87 | 2016 |
| Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein N Sugeno, T Hasegawa, N Tanaka, M Fukuda, K Wakabayashi, R Oshima, ... Journal of Biological Chemistry 289 (26), 18137-18151, 2014 | 82 | 2014 |
| Olfactory dysfunction and dementia in Parkinson's disease A Takeda, T Baba, A Kikuchi, T Hasegawa, N Sugeno, M Konno, E Miura, ... Journal of Parkinson's disease 4 (2), 181-187, 2014 | 79 | 2014 |
| Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy T Hasegawa, T Baba, M Kobayashi, M Konno, N Sugeno, A Kikuchi, ... Neurochemistry international 57 (8), 857-866, 2010 | 73 | 2010 |
| α‐Synuclein facilitates the toxicity of oxidized catechol metabolites: Implications for selective neurodegeneration in Parkinson's disease T Hasegawa, M Matsuzaki-Kobayashi, A Takeda, N Sugeno, A Kikuchi, ... FEBS letters 580 (8), 2147-2152, 2006 | 71 | 2006 |
| Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites T Hasegawa, N Sugeno, A Takeda, M Matsuzaki-Kobayashi, A Kikuchi, ... FEBS letters 581 (3), 406-412, 2007 | 69 | 2007 |
| ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways R Oshima, T Hasegawa, K Tamai, N Sugeno, S Yoshida, J Kobayashi, ... Scientific reports 6 (1), 24997, 2016 | 62 | 2016 |
| DnaJ/Hsp40 family and Parkinson's disease T Hasegawa, S Yoshida, N Sugeno, J Kobayashi, M Aoki Frontiers in neuroscience 11, 743, 2018 | 57 | 2018 |
| Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking S Yoshida, T Hasegawa, M Suzuki, N Sugeno, J Kobayashi, M Ueyama, ... Human Molecular Genetics 27 (5), 823-836, 2018 | 50 | 2018 |
| Mechanisms of neuronal death in synucleinopathy A Takeda, T Hasegawa, M Matsuzaki-Kobayashi, N Sugeno, A Kikuchi, ... BioMed Research International 2006 (1), 019365, 2006 | 50 | 2006 |
| Differentiating Parkinson’s disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test A Kikuchi, T Baba, T Hasegawa, N Sugeno, M Konno, A Takeda Parkinsonism & related disorders 17 (9), 698-700, 2011 | 49 | 2011 |
