| Function-oriented synthesis, step economy, and drug design PA Wender, VA Verma, TJ Paxton, TH Pillow Accounts of chemical research 41 (1), 40-49, 2008 | 1223 | 2008 |
| Novel antibody–antibiotic conjugate eliminates intracellular S. aureus SM Lehar, T Pillow, M Xu, L Staben, KK Kajihara, R Vandlen, L DePalatis, ... Nature 527 (7578), 323-328, 2015 | 786 | 2015 |
| The design of guanidinium-rich transporters and their internalization mechanisms PA Wender, WC Galliher, EA Goun, LR Jones, TH Pillow Advanced drug delivery reviews 60 (4-5), 452-472, 2008 | 477 | 2008 |
| Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters EA Dubikovskaya, SH Thorne, TH Pillow, CH Contag, PA Wender Proceedings of the National Academy of Sciences 105 (34), 12128-12133, 2008 | 303 | 2008 |
| Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real‐time imaging EA Goun, TH Pillow, LR Jones, JB Rothbard, PA Wender ChemBioChem 7 (10), 1497-1515, 2006 | 180 | 2006 |
| Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates LR Staben, SG Koenig, SM Lehar, R Vandlen, D Zhang, J Chuh, SF Yu, ... Nature chemistry 8 (12), 1112-1119, 2016 | 140 | 2016 |
| Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates GD Rosario Chemical Science 8 (1), 366-370, 2017 | 128 | 2017 |
| Cathepsin B is dispensable for cellular processing of cathepsin B-cleavable antibody–drug conjugates NG Caculitan, J dela Cruz Chuh, Y Ma, D Zhang, KR Kozak, Y Liu, ... Cancer research 77 (24), 7027-7037, 2017 | 126 | 2017 |
| LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity AT Krishnamurty, JA Shyer, M Thai, V Gandham, MB Buechler, YA Yang, ... Nature 611 (7934), 148-154, 2022 | 124 | 2022 |
| Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity TH Pillow, P Adhikari, RA Blake, J Chen, G Del Rosario, G Deshmukh, ... ChemMedChem 15 (1), 17-25, 2020 | 118 | 2020 |
| Site-specific trastuzumab maytansinoid antibody–drug conjugates with improved therapeutic activity through linker and antibody engineering TH Pillow, J Tien, KL Parsons-Reponte, S Bhakta, H Li, LR Staben, G Li, ... Journal of medicinal chemistry 57 (19), 7890-7899, 2014 | 108 | 2014 |
| Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice PA Wender, EA Goun, LR Jones, TH Pillow, JB Rothbard, R Shinde, ... Proceedings of the National Academy of Sciences 104 (25), 10340-10345, 2007 | 106 | 2007 |
| High-throughput cysteine scanning to identify stable antibody conjugation sites for maleimide-and disulfide-based linkers R Ohri, S Bhakta, A Fourie-O’Donohue, J dela Cruz-Chuh, SP Tsai, ... Bioconjugate Chemistry 29 (2), 473-485, 2018 | 98 | 2018 |
| Antibody-mediated delivery of chimeric BRD4 degraders. Part 2: improvement of in vitro antiproliferation activity and in vivo antitumor efficacy PS Dragovich, TH Pillow, RA Blake, JD Sadowsky, E Adaligil, P Adhikari, ... Journal of Medicinal Chemistry 64 (5), 2576-2607, 2021 | 93 | 2021 |
| Discovery of peptidomimetic antibody–drug conjugate linkers with enhanced protease specificity BQ Wei, J Gunzner-Toste, H Yao, T Wang, J Wang, Z Xu, J Chen, J Wai, ... Journal of medicinal chemistry 61 (3), 989-1000, 2018 | 90 | 2018 |
| Antibody-mediated delivery of chimeric BRD4 degraders. Part 1: exploration of antibody linker, payload loading, and payload molecular properties PS Dragovich, TH Pillow, RA Blake, JD Sadowsky, E Adaligil, P Adhikari, ... Journal of Medicinal Chemistry 64 (5), 2534-2575, 2021 | 88 | 2021 |
| Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes DS Hewings, J Heideker, TP Ma, AP AhYoung, F El Oualid, A Amore, ... Nature Communications 9 (1), 1162, 2018 | 88 | 2018 |
| Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα) PS Dragovich, P Adhikari, RA Blake, N Blaquiere, J Chen, YX Cheng, ... Bioorganic & Medicinal Chemistry Letters 30 (4), 126907, 2020 | 84 | 2020 |
| Modulating therapeutic activity and toxicity of pyrrolobenzodiazepine antibody–drug conjugates with self-immolative disulfide linkers TH Pillow, M Schutten, SF Yu, R Ohri, J Sadowsky, KA Poon, W Solis, ... Molecular cancer therapeutics 16 (5), 871-878, 2017 | 79 | 2017 |
| Modulating antibody–drug conjugate payload metabolism by conjugation site and linker modification D Su, KR Kozak, J Sadowsky, SF Yu, A Fourie-O’Donohue, C Nelson, ... Bioconjugate Chemistry 29 (4), 1155-1167, 2018 | 68 | 2018 |
