Следене
Molly Gasperini
Molly Gasperini
Потвърден имейл адрес: uw.edu
Заглавие
Позовавания
Позовавания
Година
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith, M Gasperini, ...
Nature 562 (7726), 217-222, 2018
4312018
A genome-wide framework for mapping gene regulation via cellular genetic screens
M Gasperini, AJ Hill, JL McFaline-Figueroa, B Martin, S Kim, MD Zhang, ...
Cell 176 (1-2), 377-390. e19, 2019
2942019
Towards a comprehensive catalogue of validated and target-linked human enhancers
M Gasperini, JM Tome, J Shendure
Nature Reviews Genetics 21 (5), 292-310, 2020
1462020
MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation
MS Alexander, G Kawahara, N Motohashi, JC Casar, I Eisenberg, ...
Cell Death & Differentiation 20 (9), 1194-1208, 2013
1352013
MicroRNA-486–dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy–associated symptoms
MS Alexander, JC Casar, N Motohashi, NM Vieira, I Eisenberg, ...
The Journal of clinical investigation 124 (6), 2651-2667, 2014
1232014
CRISPR/Cas9-mediated scanning for regulatory elements required for HPRT1 expression via thousands of large, programmed genomic deletions
M Gasperini, GM Findlay, A McKenna, JH Milbank, C Lee, MD Zhang, ...
The American Journal of Human Genetics 101 (2), 192-205, 2017
1152017
On the design of CRISPR-based single-cell molecular screens
AJ Hill, JL McFaline-Figueroa, LM Starita, MJ Gasperini, KA Matreyek, ...
Nature methods 15 (4), 271-274, 2018
1052018
The power of multiplexed functional analysis of genetic variants
M Gasperini, L Starita, J Shendure
Nature protocols 11 (10), 1782-1787, 2016
1022016
Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia
C Rippey, T Walsh, S Gulsuner, M Brodsky, AS Nord, M Gasperini, ...
The American Journal of Human Genetics 93 (4), 697-710, 2013
452013
Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing
JS Bloom, L Sathe, C Munugala, EM Jones, M Gasperini, NB Lubock, ...
MedRxiv, 2020
402020
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling
G Kawahara, MJ Gasperini, JA Myers, JJ Widrick, A Eran, PR Serafini, ...
Human molecular genetics 23 (7), 1869-1878, 2014
402014
Identifying novel enhancer elements with CRISPR-based screens
JC Klein, W Chen, M Gasperini, J Shendure
ACS chemical biology 13 (2), 326-332, 2018
202018
Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples
JS Bloom, L Sathe, C Munugala, EM Jones, M Gasperini, NB Lubock, ...
Nature Biomedical Engineering 5 (7), 657-665, 2021
162021
Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A
MS Alexander, MJ Gasperini, PT Tsai, DE Gibbs, JM Spinazzola, ...
Translational psychiatry 6 (9), e901-e901, 2016
122016
crisprQTL mapping as a genome-wide association framework for cellular genetic screens
M Gasperini, AJ Hill, JL McFaline-Figueroa, B Martin, C Trapnell, N Ahituv, ...
BioRxiv, 314344, 2018
82018
Accurate functional classification of thousands of BRCA1 variants with saturation genome editing
GM Findlay, R Daza, BK Martin, MD Zhang, AP Leith, M Gasperini, ...
bioRxiv, 2019
42019
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling
G Kawahara, MJ Gasperini, JA Myers, JJ Widrick, A Eran, PR Serafini, ...
Human Molecular Genetics 24 (15), 4480-4481, 2015
32015
Paired CRISPR/Cas9 guide-RNAs enable high-throughput deletion scanning (ScanDel) of a Mendelian disease locus for functionally critical non-coding elements
M Gasperini, GM Findlay, A McKenna, JH Milbank, C Lee, MD Zhang, ...
bioRxiv, 092445, 2016
22016
CRISPR-QTL mapping as a genome-wide association framework for cellular genetic screens of the noncoding genome
M Gasperini, A Hill, JL Figueroa, B Martin, C Trapnell, N Ahituv, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 749-750, 2019
2019
Efficiently searching for enhancers and their target genes in the human genome
MJ Gasperini
2019
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Статии 1–20