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Leslie Gewin
Leslie Gewin
Vanderbilt University Medical Center
Verified email at vumc.org
Title
Cited by
Cited by
Year
β1 integrin expression by podocytes is required to maintain glomerular structural integrity
A Pozzi, G Jarad, GW Moeckel, S Coffa, X Zhang, L Gewin, V Eremina, ...
Developmental biology 316 (2), 288-301, 2008
2202008
Renal fibrosis: primacy of the proximal tubule
LS Gewin
Matrix Biology 68, 248-262, 2018
1892018
Progression of chronic kidney disease: too much cellular talk causes damage
L Gewin, R Zent, A Pozzi
Kidney international 91 (3), 552-560, 2017
1442017
How does TGF-β mediate tubulointerstitial fibrosis?
L Gewin, R Zent
Seminars in nephrology 32 (3), 228-235, 2012
1042012
TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration
S Chung, JM Overstreet, Y Li, Y Wang, A Niu, S Wang, X Fan, K Sasaki, ...
JCI insight 3 (21), 2018
922018
Deleting the TGF-β receptor attenuates acute proximal tubule injury
L Gewin, S Vadivelu, S Neelisetty, MB Srichai, P Paueksakon, A Pozzi, ...
Journal of the American Society of Nephrology 23 (12), 2001-2011, 2012
892012
Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells
S Neelisetty, C Alford, K Reynolds, L Woodbury, S Nlandu-Khodo, H Yang, ...
Kidney international 88 (3), 503-514, 2015
812015
β1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity
X Zhang, G Mernaugh, DH Yang, L Gewin, MB Srichai, RC Harris, ...
Development 136 (19), 3357-3366, 2009
812009
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
S Kishi, CR Brooks, K Taguchi, T Ichimura, Y Mori, A Akinfolarin, N Gupta, ...
The Journal of clinical investigation 129 (11), 4797-4816, 2019
782019
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling
X Chen, H Wang, HJ Liao, W Hu, L Gewin, G Mernaugh, S Zhang, ...
The Journal of clinical investigation 124 (8), 3295-3310, 2014
732014
Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis
JM Overstreet, Y Wang, X Wang, A Niu, LS Gewin, B Yao, RC Harris, ...
The FASEB Journal 31 (10), 4407, 2017
652017
Pharmacologic blockade of αvβ1 integrin ameliorates renal failure and fibrosis in vivo
Y Chang, WL Lau, H Jo, K Tsujino, L Gewin, NI Reed, A Atakilit, ...
Journal of the American Society of Nephrology 28 (7), 1998-2005, 2017
592017
Blocking TGF-β and β-catenin epithelial crosstalk exacerbates CKD
S Nlandu-Khodo, S Neelisetty, M Phillips, M Manolopoulou, G Bhave, ...
Journal of the American Society of Nephrology 28 (12), 3490-3503, 2017
572017
Sugar or fat? Renal tubular metabolism reviewed in health and disease
LS Gewin
Nutrients 13 (5), 1580, 2021
562021
TGF-β receptor deletion in the renal collecting system exacerbates fibrosis
L Gewin, N Bulus, G Mernaugh, G Moeckel, RC Harris, HL Moses, A Pozzi, ...
Journal of the American Society of Nephrology 21 (8), 1334-1343, 2010
542010
Wnt/β-catenin in acute kidney injury and progression to chronic kidney disease
T Huffstater, WD Merryman, LS Gewin
Seminars in nephrology 40 (2), 126-137, 2020
472020
Cytometry‐based single‐cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF‐α‐induced apoptosis in vivo
AJ Simmons, A Banerjee, ET McKinley, CR Scurrah, CA Herring, ...
Molecular systems biology 11 (10), 835, 2015
442015
Transforming growth factor-β in the acute kidney injury to chronic kidney disease transition
LS Gewin
Nephron 143 (3), 154-157, 2019
392019
Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model
S Colon, H Luan, Y Liu, C Meyer, L Gewin, G Bhave
American Journal of Physiology-Renal Physiology 316 (2), F360-F371, 2019
352019
Renal tubule repair: is Wnt/β-catenin a friend or foe?
LS Gewin
Genes 9 (2), 58, 2018
312018
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