Sara S. Rinne
Sara S. Rinne
Postdoctoral Associate at Weill Cornell Medicine
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Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
B Mitran, Z Varasteh, A Abouzayed, SS Rinne, E Puuvuori, M De Rosa, ...
Cancers 11 (9), 1371, 2019
Trastuzumab cotreatment improves survival of mice with PC‐3 prostate cancer xenografts treated with the GRPR antagonist 177Lu‐DOTAGA‐PEG2‐RM26
B Mitran, SS Rinne, MW Konijnenberg, T Maina, BA Nock, M Altai, ...
International journal of cancer 145 (12), 3347-3358, 2019
Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2
A Vorobyeva, A Sсhulga, E Konovalova, R Güler, B Mitran, J Garousi, ...
International journal of oncology 54 (4), 1209-1220, 2019
Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
B Mitran, R Güler, FP Roche, E Lindström, RK Selvaraju, F Fleetwood, ...
Theranostics 8 (16), 4462, 2018
Indirect radioiodination of DARPin G3 using N-succinimidyl-para-iodobenzoate improves the contrast of HER2 molecular imaging
A Vorobyeva, A Schulga, SS Rinne, T Günther, A Orlova, S Deyev, ...
International journal of molecular sciences 20 (12), 3047, 2019
Pet and spect imaging of the egfr family (Rtk class i) in oncology
SS Rinne, A Orlova, V Tolmachev
International Journal of Molecular Sciences 22 (7), 3663, 2021
Heterodimeric radiotracer targeting PSMA and GRPR for imaging of prostate cancer—optimization of the affinity towards PSMA by linker modification in murine model
F Lundmark, A Abouzayed, B Mitran, SS Rinne, Z Varasteh, M Larhed, ...
Pharmaceutics 12 (7), 614, 2020
On the prevention of kidney uptake of radiolabeled DARPins
M Altai, J Garousi, SS Rinne, A Schulga, S Deyev, A Vorobyeva
EJNMMI research 10 (1), 1-8, 2020
Feasibility of imaging EpCAM expression in ovarian cancer using radiolabeled DARPin Ec1
A Vorobyeva, E Konovalova, T Xu, A Schulga, M Altai, J Garousi, ...
International journal of molecular sciences 21 (9), 3310, 2020
Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111
SS Rinne, CD Leitao, B Mitran, TZ Bass, KG Andersson, V Tolmachev, ...
Scientific reports 9 (1), 1-11, 2019
Influence of molecular design on the targeting properties of ABD-fused mono-and bi-valent anti-HER3 affibody therapeutic constructs
M Altai, CD Leitao, SS Rinne, A Vorobyeva, C Atterby, S Ståhl, ...
Cells 7 (10), 164, 2018
Molecular design of HER3-targeting affibody molecules: Influence of chelator and presence of HEHEHE-tag on biodistribution of 68Ga-labeled tracers
C Dahlsson Leitao, SS Rinne, B Mitran, A Vorobyeva, KG Andersson, ...
International journal of molecular sciences 20 (5), 1080, 2019
Evaluation of the therapeutic potential of a HER3-binding affibody construct TAM-HER3 in comparison with a monoclonal antibody, seribantumab
A Orlova, TZ Bass, SS Rinne, CD Leitao, M Rosestedt, C Atterby, ...
Molecular pharmaceutics 15 (8), 3394-3403, 2018
Incorporation of a hydrophilic spacer reduces hepatic uptake of HER2-targeting affibody–DM1 drug conjugates
H Ding, M Altai, SS Rinne, A Vorobyeva, V Tolmachev, T Gräslund, ...
Cancers 11 (8), 1168, 2019
Synthesis and preclinical evaluation of radio-iodinated GRPR/PSMA bispecific heterodimers for the theranostics application in prostate cancer
A Abouzayed, CB Yim, B Mitran, SS Rinne, V Tolmachev, M Larhed, ...
Pharmaceutics 11 (7), 358, 2019
Preclinical Evaluation of 99mTc-ZHER2: 41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake
M Oroujeni, SS Rinne, A Vorobyeva, A Loftenius, J Feldwisch, ...
International journal of molecular sciences 22 (5), 2770, 2021
Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26
B Mitran, H Thisgaard, S Rinne, JH Dam, F Azami, V Tolmachev, A Orlova, ...
Scientific reports 9 (1), 1-11, 2019
66 Ga-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [66 Ga] Ga-NOTA-PEG 2-RM26
SS Rinne, A Abouzayed, K Gagnon, V Tolmachev, A Orlova
Scientific reports 11 (1), 1-12, 2021
Increase in negative charge of 68 Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules
SS Rinne, CD Leitao, J Gentry, B Mitran, A Abouzayed, V Tolmachev, ...
Scientific reports 9 (1), 1-10, 2019
The Use of a Non-Conventional Long-Lived Gallium Radioisotope 66Ga Improves Imaging Contrast of EGFR Expression in Malignant Tumours Using DFO-ZEGFR: 2377 Affibody Molecule
M Oroujeni, T Xu, K Gagnon, SS Rinne, J Weis, J Garousi, KG Andersson, ...
Pharmaceutics 13 (2), 292, 2021
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