Gerald V Denis
Gerald V Denis
Потвърден имейл адрес: bu.edu
BET domain co-regulators in obesity, inflammation and cancer
AC Belkina, GV Denis
Nature reviews Cancer 12 (7), 465-477, 2012
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile
J DeFuria, AC Belkina, M Jagannathan-Bogdan, J Snyder-Cappione, ...
Proceedings of the National Academy of Sciences 110 (13), 5133-5138, 2013
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
AC Belkina, BS Nikolajczyk, GV Denis
The Journal of Immunology 190 (7), 3670-3678, 2013
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1
C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ...
Journal of leukocyte biology 92 (6), 1147-1154, 2012
Brd2 disruption in mice causes severe obesity without Type 2 diabetes
F Wang, H Liu, WP Blanton, A Belkina, NK Lebrasseur, GV Denis
Biochemical Journal 425 (1), 71-85, 2010
Clinical trials for BET inhibitors run ahead of the science
G Andrieu, AC Belkina, GV Denis
Drug Discovery Today: Technologies 19, 45-50, 2016
‘Metabolically healthy obesity’: origins and implications
GV Denis, MS Obin
Molecular aspects of medicine 34 (1), 59-70, 2013
RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F
GV Denis, C Vaziri, N Guo, DV Faller
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes
J You, V Srinivasan, GV Denis, WJ Harrington Jr, ME Ballestas, KM Kaye, ...
Journal of virology 80 (18), 8909-8919, 2006
Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines
GV Denis, ME McComb, DV Faller, A Sinha, PB Romesser, CE Costello
Journal of proteome research 5 (3), 502-511, 2006
A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator.
GV Denis, MR Green
Genes & development 10 (3), 261-271, 1996
Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia
RJ Greenwald, JR Tumang, A Sinha, N Currier, RD Cardiff, TL Rothstein, ...
Blood 103 (4), 1475-1484, 2004
Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A
A Sinha, DV Faller, GV Denis
Biochemical Journal 387 (1), 257-269, 2005
Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation
GV Denis
Discovery medicine 10 (55), 489, 2010
BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling
G Andrieu, AH Tran, KJ Strissel, GV Denis
Cancer research 76 (22), 6555-6567, 2016
Metabolic disease risk in children by salivary biomarker analysis
JM Goodson, A Kantarci, ML Hartman, GV Denis, D Stephens, H Hasturk, ...
PloS one 9 (6), e98799, 2014
Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor …
J Chung, V Karkhanis, S Tae, F Yan, P Smith, LW Ayers, C Agostinelli, ...
Journal of Biological Chemistry 288 (49), 35534-35547, 2013
Metabolic health reduces risk of obesity-related cancer in framingham study adults
LL Moore, S Chadid, MR Singer, BE Kreger, GV Denis
Cancer Epidemiology, Biomarkers & Prevention 23 (10), 2057-2065, 2014
Obesity genes and insulin resistance
AC Belkina, GV Denis
Current Opinion in Endocrinology, Diabetes and Obesity 17 (5), 472-477, 2010
BET bromodomain proteins Brd2, Brd3 and Brd4 selectively regulate metabolic pathways in the pancreatic β-cell
JT Deeney, AC Belkina, OS Shirihai, BE Corkey, GV Denis
PloS one 11 (3), e0151329, 2016
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