Gerald V Denis
Gerald V Denis
Потвърден имейл адрес: bu.edu
BET domain co-regulators in obesity, inflammation and cancer
AC Belkina, GV Denis
Nature reviews Cancer 12 (7), 465-477, 2012
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile
J DeFuria, AC Belkina, M Jagannathan-Bogdan, J Snyder-Cappione, ...
Proceedings of the National Academy of Sciences 110 (13), 5133-5138, 2013
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
AC Belkina, BS Nikolajczyk, GV Denis
The Journal of Immunology 190 (7), 3670-3678, 2013
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1
C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ...
Journal of leukocyte biology 92 (6), 1147-1154, 2012
Brd2 disruption in mice causes severe obesity without Type 2 diabetes
F Wang, H Liu, WP Blanton, A Belkina, NK Lebrasseur, GV Denis
Biochemical Journal 425 (1), 71-85, 2010
Clinical trials for BET inhibitors run ahead of the science
G Andrieu, AC Belkina, GV Denis
Drug Discovery Today: Technologies 19, 45-50, 2016
‘Metabolically healthy obesity’: origins and implications
GV Denis, MS Obin
Molecular aspects of medicine 34 (1), 59-70, 2013
RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F
GV Denis, C Vaziri, N Guo, DV Faller
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes
J You, V Srinivasan, GV Denis, WJ Harrington Jr, ME Ballestas, KM Kaye, ...
Journal of virology 80 (18), 8909-8919, 2006
A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator
GV Denis, MR Green
Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines
GV Denis, ME McComb, DV Faller, A Sinha, PB Romesser, CE Costello
Journal of proteome research 5 (3), 502-511, 2006
Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia
RJ Greenwald, JR Tumang, A Sinha, N Currier, RD Cardiff, TL Rothstein, ...
Blood 103 (4), 1475-1484, 2004
Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A
A Sinha, DV Faller, GV Denis
Biochemical Journal 387 (1), 257-269, 2005
Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation
GV Denis
Discovery medicine 10 (55), 489, 2010
BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling
G Andrieu, AH Tran, KJ Strissel, GV Denis
Cancer research 76 (22), 6555-6567, 2016
Metabolic disease risk in children by salivary biomarker analysis
JM Goodson, A Kantarci, ML Hartman, GV Denis, D Stephens, H Hasturk, ...
PloS one 9 (6), e98799, 2014
Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor …
J Chung, V Karkhanis, S Tae, F Yan, P Smith, LW Ayers, C Agostinelli, ...
Journal of Biological Chemistry 288 (49), 35534-35547, 2013
Metabolic health reduces risk of obesity-related cancer in framingham study adults
LL Moore, S Chadid, MR Singer, BE Kreger, GV Denis
Cancer Epidemiology, Biomarkers & Prevention 23 (10), 2057-2065, 2014
Obesity genes and insulin resistance
AC Belkina, GV Denis
Current opinion in endocrinology, diabetes, and obesity 17 (5), 472, 2010
BET bromodomain proteins Brd2, Brd3 and Brd4 selectively regulate metabolic pathways in the pancreatic β-cell
JT Deeney, AC Belkina, OS Shirihai, BE Corkey, GV Denis
PLoS One 11 (3), e0151329, 2016
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