Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses J Zhu, B Min, J Hu-Li, CJ Watson, A Grinberg, Q Wang, N Killeen, ... Nature immunology 5 (11), 1157-1165, 2004 | 847 | 2004 |
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors J Zhu, H Yamane, J Cote-Sierra, L Guo, WE Paul Cell research 16 (1), 3-10, 2006 | 659 | 2006 |
IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells Y Huang, L Guo, J Qiu, X Chen, J Hu-Li, U Siebenlist, PR Williamson, ... Nature immunology 16 (2), 161-169, 2015 | 637 | 2015 |
Interleukin 2 plays a central role in Th2 differentiation J Cote-Sierra, G Foucras, L Guo, L Chiodetti, HA Young, J Hu-Li, J Zhu, ... Proceedings of the National Academy of Sciences 101 (11), 3880-3885, 2004 | 540 | 2004 |
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells L Guo, G Wei, J Zhu, W Liao, WJ Leonard, K Zhao, W Paul Proceedings of the National Academy of Sciences 106 (32), 13463-13468, 2009 | 492 | 2009 |
Stat5 activation plays a critical role in Th2 differentiation J Zhu, J Cote-Sierra, L Guo, WE Paul Immunity 19 (5), 739-748, 2003 | 479 | 2003 |
Stat6 is necessary and sufficient for IL-4’s role in Th2 differentiation and cell expansion J Zhu, L Guo, CJ Watson, J Hu-Li, WE Paul The Journal of Immunology 166 (12), 7276-7281, 2001 | 394 | 2001 |
The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses J Zhu, D Jankovic, AJ Oler, G Wei, S Sharma, G Hu, L Guo, R Yagi, ... Immunity 37 (4), 660-673, 2012 | 376 | 2012 |
Developmental acquisition of regulomes underlies innate lymphoid cell functionality HY Shih, G Sciumè, Y Mikami, L Guo, HW Sun, SR Brooks, JF Urban, ... Cell 165 (5), 1120-1133, 2016 | 315 | 2016 |
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation J Zhu, L Guo, B Min, CJ Watson, J Hu-Li, HA Young, PN Tsichlis, WE Paul Immunity 16 (5), 733-744, 2002 | 245 | 2002 |
Innate immunological function of TH2 cells in vivo L Guo, Y Huang, X Chen, J Hu-Li, JF Urban Jr, WE Paul Nature immunology 16 (10), 1051-1059, 2015 | 183 | 2015 |
Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene J Hu-Li, C Pannetier, L Guo, M Löhning, H Gu, C Watson, M Assenmacher, ... Immunity 14 (1), 1-11, 2001 | 169 | 2001 |
Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP T Takizawa, PR Gudla, L Guo, S Lockett, T Misteli Genes & development 22 (4), 489-498, 2008 | 168 | 2008 |
Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cells J Zhu, TS Davidson, G Wei, D Jankovic, K Cui, DE Schones, L Guo, ... Journal of Experimental Medicine 206 (2), 329-341, 2009 | 163 | 2009 |
Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion J Zhu, D Jankovic, A Grinberg, L Guo, WE Paul Proceedings of the National Academy of Sciences 103 (48), 18214-18219, 2006 | 129 | 2006 |
Cytokine-induced cytokine production by conventional and innate lymphoid cells L Guo, IS Junttila, WE Paul Trends in immunology 33 (12), 598-606, 2012 | 115 | 2012 |
In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production L Guo, J Hu-Li, J Zhu, CJ Watson, MJ Difilippantonio, C Pannetier, ... Proceedings of the National Academy of Sciences 99 (16), 10623-10628, 2002 | 98 | 2002 |
Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus L Guo, J Hu-Li, WE Paul Immunity 20 (2), 193-203, 2004 | 90 | 2004 |
Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13 L Guo, J Hu-Li, WE Paul Immunity 23 (1), 89-99, 2005 | 84 | 2005 |
Transient inhibition of interleukin 4 signaling by T cell receptor ligation J Zhu, H Huang, L Guo, T Stonehouse, CJ Watson, J Hu-Li, WE Paul The Journal of experimental medicine 192 (8), 1125-1134, 2000 | 81 | 2000 |