Следене
John Whittaker
John Whittaker
Professor of Biostatistics, University of Cambridge
Потвърден имейл адрес: mrc-bsu.cam.ac.uk
Заглавие
Позовавания
Позовавания
Година
The support of human genetic evidence for approved drug indications
MR Nelson, H Tipney, JL Painter, J Shen, P Nicoletti, Y Shen, A Floratos, ...
Nature genetics 47 (8), 856-860, 2015
12662015
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts
KS Vimaleswaran, DJ Berry, C Lu, E Tikkanen, S Pilz, LT Hiraki, ...
PLoS medicine 10 (2), e1001383, 2013
11872013
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium
The Lancet 379 (9822), 1214-1224, 2012
10472012
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, ...
Bmj 349, g4164, 2014
7982014
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people
MR Nelson, D Wegmann, MG Ehm, D Kessner, PS Jean, C Verzilli, ...
Science 337 (6090), 100-104, 2012
7972012
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
DI Swerdlow, D Preiss, KB Kuchenbaecker, MV Holmes, JEL Engmann, ...
The Lancet 385 (9965), 351-361, 2015
7282015
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
C Reactive Protein Coronary Heart Disease Genetics Collaboration
Bmj 342, 2011
6632011
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study
PJ Talmud, S Shah, R Whittall, M Futema, P Howard, JA Cooper, ...
The Lancet 381 (9874), 1293-1301, 2013
6422013
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
N Hubner, CA Wallace, H Zimdahl, E Petretto, H Schulz, F Maciver, ...
Nature genetics 37 (3), 243-253, 2005
6282005
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study
KS Vimaleswaran, A Cavadino, DJ Berry, R Jorde, AK Dieffenbach, C Lu, ...
The lancet Diabetes & endocrinology 2 (9), 719-729, 2014
4422014
Marker-assisted selection using ridge regression
JC Whittaker, R Thompson, MC Denham
Genetics Research 75 (2), 249-252, 2000
4222000
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
MV Holmes, P Newcombe, JA Hubacek, R Sofat, SL Ricketts, J Cooper, ...
The Lancet 378 (9791), 584-594, 2011
4172011
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies
CJ Hoggart, JC Whittaker, M De Iorio, DJ Balding
PLoS genetics 4 (7), e1000130, 2008
4042008
Exome sequencing and characterization of 49,960 individuals in the UK Biobank
CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ...
Nature 586 (7831), 749-756, 2020
3822020
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ...
Nature genetics 51 (3), 481-493, 2019
3712019
Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus
AI Russell, DS Cunninghame Graham, C Shepherd, CA Roberton, ...
Human molecular genetics 13 (1), 137-147, 2004
3692004
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy
SWC Van Mil, A Milona, PH Dixon, R Mullenbach, VL Geenes, ...
Gastroenterology 133 (2), 507-516, 2007
2972007
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci
FW Asselbergs, Y Guo, EPA Van Iperen, S Sivapalaratnam, V Tragante, ...
The American Journal of Human Genetics 91 (5), 823-838, 2012
2962012
HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer
CF Spraggs, LR Budde, LP Briley, N Bing, CJ Cox, KS King, JC Whittaker, ...
Journal of Clinical Oncology 29 (6), 667-673, 2011
2952011
Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia
MC Clarke, A Tanskanen, M Huttunen, JC Whittaker, M Cannon
American Journal of Psychiatry 166 (9), 1025-1030, 2009
2932009
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