David Kirsch
David Kirsch
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Cited by
Cited by
Restoration of p53 function leads to tumour regression in vivo
A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ...
Nature 445 (7128), 661-665, 2007
Conversion of Bcl-2 to a Bax-like death effector by caspases
EHY Cheng, DG Kirsch, RJ Clem, R Ravi, MB Kastan, A Bedi, K Ueno, ...
Science 278 (5345), 1966-1968, 1997
Modulation of cell death by Bcl-xL through caspase interaction
RJ Clem, EHY Cheng, CL Karp, DG Kirsch, K Ueno, A Takahashi, ...
Proceedings of the National Academy of Sciences 95 (2), 554-559, 1998
Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c
DG Kirsch, A Doseff, BN Chau, DS Lim, NC de Souza-Pinto, R Hansford, ...
Journal of Biological Chemistry 274 (30), 21155-21161, 1999
Dicer1 functions as a haploinsufficient tumor suppressor
MS Kumar, RE Pester, CY Chen, K Lane, C Chin, J Lu, DG Kirsch, ...
Genes & development 23 (23), 2700-2704, 2009
Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2–positive breast cancer
NU Lin, LA Carey, MC Liu, J Younger, SE Come, M Ewend, GJ Harris, ...
Journal of clinical oncology 26 (12), 1993-1999, 2008
Animal models for medical countermeasures to radiation exposure
JP Williams, SL Brown, GE Georges, M Hauer-Jensen, RP Hill, AK Huser, ...
Radiation research 173 (4), 557-578, 2010
Dietary methionine influences therapy in mouse cancer models and alters human metabolism
X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ...
Nature 572 (7769), 397-401, 2019
Strategies for optimizing the response of cancer and normal tissues to radiation
EJ Moding, MB Kastan, DG Kirsch
Nature reviews Drug discovery 12 (7), 526-542, 2013
Tumor-suppressor p53: implications for tumor development and prognosis.
DG Kirsch, MB Kastan
Journal of clinical oncology 16 (9), 3158-3168, 1998
Metabolomics in cancer research and emerging applications in clinical oncology
DR Schmidt, R Patel, DG Kirsch, CA Lewis, MG Vander Heiden, ...
CA: a cancer journal for clinicians 71 (4), 333-358, 2021
A spatially and temporally restricted mouse model of soft tissue sarcoma
DG Kirsch, DM Dinulescu, JB Miller, J Grimm, PM Santiago, NP Young, ...
Nature medicine 13 (8), 992-997, 2007
Treatment and outcome of 82 patients with angiosarcoma
JA Abraham, FJ Hornicek, AM Kaufman, DC Harmon, DS Springfield, ...
Annals of surgical oncology 14, 1953-1967, 2007
Acetate production from glucose and coupling to mitochondrial metabolism in mammals
X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao, MA Reid, J Liu, ...
Cell 175 (2), 502-513. e13, 2018
A plasmonic gold nanostar theranostic probe for in vivo tumor imaging and photothermal therapy
Y Liu, JR Ashton, EJ Moding, H Yuan, JK Register, AM Fales, J Choi, ...
Theranostics 5 (9), 946, 2015
Significant reduction of late toxicities in patients with extremity sarcoma treated with image-guided radiation therapy to a reduced target volume: results of radiation therapy …
D Wang, Q Zhang, BL Eisenberg, JM Kane, XA Li, D Lucas, IA Petersen, ...
Journal of clinical oncology 33 (20), 2231-2238, 2015
Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis
TSK Eisinger-Mathason, M Zhang, Q Qiu, N Skuli, MS Nakazawa, ...
Cancer discovery 3 (10), 1190-1205, 2013
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis
DG Kirsch, PM Santiago, E di Tomaso, JM Sullivan, WS Hou, T Dayton, ...
Science 327 (5965), 593, 2010
Preoperative or postoperative radiotherapy versus surgery alone for retroperitoneal sarcoma: a case-control, propensity score-matched analysis of a nationwide clinical oncology …
DP Nussbaum, CN Rushing, WO Lane, DM Cardona, DG Kirsch, ...
The lancet oncology 17 (7), 966-975, 2016
A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer
MJ Whitley, DM Cardona, AL Lazarides, I Spasojevic, JM Ferrer, J Cahill, ...
Science translational medicine 8 (320), 320ra4-320ra4, 2016
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