| mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex JT Cunningham, JT Rodgers, DH Arlow, F Vazquez, VK Mootha, ... nature 450 (7170), 736-740, 2007 | 1712 | 2007 |
| ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ... The Journal of clinical investigation 122 (12), 4621-4634, 2012 | 442 | 2012 |
| Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer JT Cunningham, MV Moreno, A Lodi, SM Ronen, D Ruggero Cell 157 (5), 1088-1103, 2014 | 255 | 2014 |
| Translation control of the immune checkpoint in cancer and its therapeutic targeting Y Xu, M Poggio, HY Jin, Z Shi, CM Forester, Y Wang, CR Stumpf, L Xue, ... Nature medicine 25 (2), 301-311, 2019 | 236 | 2019 |
| Development of a stress response therapy targeting aggressive prostate cancer HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ... Science translational medicine 10 (439), eaar2036, 2018 | 153 | 2018 |
| Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling SM Blättler, JT Cunningham, F Verdeguer, H Chim, W Haas, H Liu, ... Cell metabolism 15 (4), 505-517, 2012 | 108 | 2012 |
| Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle SM Blättler, F Verdeguer, M Liesa, JT Cunningham, RO Vogel, H Chim, ... Molecular and cellular biology 32 (16), 3333-3346, 2012 | 96 | 2012 |
| Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin C Truillet, JT Cunningham, MFL Parker, LT Huynh, CS Conn, D Ruggero, ... Clinical Cancer Research 23 (12), 3045-3052, 2017 | 29 | 2017 |
| POPULATION GENETICS OF RESURGENCE: WHITE-TAILED DEER IN KENTUCKY KC Doerner, W Braden, J Cork, T Cunningham, A Rice, BJ Furman, ... Journal of Wildlife Management 69 (1), 345-355, 2005 | 26 | 2005 |
| Tobacco smoking induces metabolic reprogramming of renal cell carcinoma J Reigle, D Secic, J Biesiada, C Wetzel, B Shamsaei, J Chu, Y Zang, ... The Journal of clinical investigation 131 (1), 2021 | 19 | 2021 |
| New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization JT Cunningham, D Ruggero Cancer discovery 3 (10), 1099-1102, 2013 | 18 | 2013 |
| Molecular and metabolic subtypes in sporadic and inherited clear cell renal cell carcinoma MF Czyzyk-Krzeska, JA Landero Figueroa, S Gulati, JT Cunningham, ... Genes 12 (3), 388, 2021 | 13 | 2021 |
| Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms F Verdeguer, SM Blättler, JT Cunningham, JA Hall, H Chim, P Puigserver Molecular Endocrinology 28 (3), 308-316, 2014 | 13 | 2014 |
| Investigating Myc-dependent translational regulation in normal and cancer cells JT Cunningham, M Pourdehnad, CR Stumpf, D Ruggero The Myc Gene: Methods and Protocols, 201-212, 2013 | 10 | 2013 |
| Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma ME Bischoff, B Shamsaei, J Yang, D Secic, B Vemuri, JA Reisz, ... Cancer Discovery, 2024 | | 2024 |
| Evolutionary origins and innovations sculpting the mammalian PRPS enzyme complex B Karki, AC Macmillan, S Vicente-Munoz, KD Greis, LE Romick, ... bioRxiv, 2024.10. 01.616059, 2024 | | 2024 |
| Complimentary transcriptomic-metallomic analysis identifies risk of relapse for clear-cell renal cell carcinoma (ccRCC) patients. S Gulati, B Vemuri, D Secic, B Shamsaei, DR Plas, JT Cunningham, ... Journal of Clinical Oncology 40 (6_suppl), 378-378, 2022 | | 2022 |
| Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking MF Czyzyk-Krzeska, J Meller, JA Landero Figueroa, DR Plas, ... Molecular & Cellular Oncology 8 (2), 1859917, 2021 | | 2021 |
| Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment D Ruggero, JT Cunningham US Patent 9,765,337, 2017 | | 2017 |
| Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ... Cancer Research 77 (6_Supplement), A25-A25, 2017 | | 2017 |
