Purification of Lumbricus terrestris Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications C Savla, C Munoz, R Hickey, M Belicak, C Gilbert, P Cabrales, AF Palmer ACS biomaterials science & engineering 6 (9), 4957-4968, 2020 | 18 | 2020 |
Structural stability and biophysical properties of the mega-protein erythrocruorin are regulated by polyethylene glycol surface coverage C Savla, AF Palmer Biomacromolecules 22 (5), 2081-2093, 2021 | 10 | 2021 |
Poly (ethylene glycol) surface-conjugated apohemoglobin as a synthetic heme scavenger IS Pires, C Savla, AF Palmer Biomacromolecules 21 (6), 2155-2164, 2020 | 10 | 2020 |
Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross‐link density X Gu, C Bolden‐Rush, CT Cuddington, DA Belcher, C Savla, IS Pires, ... Biotechnology and bioengineering 117 (8), 2362-2376, 2020 | 9 | 2020 |
Tangential flow filtration facilitated fractionation and PEGylation of low and high‐molecular weight polymerized hemoglobins and their biophysical properties X Gu, C Savla, AF Palmer Biotechnology and bioengineering 119 (1), 176-186, 2022 | 7 | 2022 |
Purification and analysis of a protein cocktail capable of scavenging cell‐free hemoglobin, heme, and iron IS Pires, K Govender, CJ Munoz, AT Williams, QT O'Boyle, C Savla, ... Transfusion 61 (6), 1894-1907, 2021 | 6 | 2021 |
Enhanced photodynamic therapy using the apohemoglobin-haptoglobin complex as a carrier of aluminum phthalocyanine IS Pires, QT O’Boyle, CJ Munoz, C Savla, P Cabrales, AF Palmer ACS Applied Bio Materials 3 (7), 4495-4506, 2020 | 4 | 2020 |
Photocatalytic synthesis of a polydopamine-coated acellular mega-hemoglobin as a potential oxygen therapeutic with antioxidant properties E Pozy, C Savla, AF Palmer Biomacromolecules 24 (5), 2022-2029, 2023 | 2 | 2023 |
Lyophilized annelid mega-hemoglobin retains its’ quaternary structure and oxygen equilibrium properties after room temperature storage for over 6 months C Savla, AF Palmer Plos one 17 (2), e0263996, 2022 | 2 | 2022 |
Colloidally stable heme-albumin complexes and methods of making and using thereof A Palmer, C Savla US Patent WO2023201107A1, 2023 | | 2023 |
Biocompatibility of the oxygen carrier polymerized human hemoglobin towards HepG2/C3A cells N Chen, DA Belcher, C Savla, AF Palmer, F Berthiaume Heliyon 9 (5), 2023 | | 2023 |
Scalable Purification of Ultra-Pure Lumbricus terrestris Mega-Hemoglobin and Surface Modification using Bio-compatible Polymers for use as an Oxygen Therapeutic C Savla The Ohio State University, 2023 | | 2023 |
Hemoglobin-based oxygen carriers and methods of making and using thereof A Palmer, PJ Cabrales Arevalo, X Gu, C Savla US Patent WO2022272124A1, 2022 | | 2022 |
Scalable manufacturing platform for the production of PEGylated heme albumin C Savla, AF Palmer Biotechnology and bioengineering 119 (12), 3612-3622, 2022 | | 2022 |
Bio-Compatible Polymer-Conjugated Extracellular Mega-Hemoglobin for Diverse Oxygen Therapeutic Applications C Savla 2022 AIChE Annual Meeting, 2022 | | 2022 |
Photocatalytic Synthesis of a Novel Polydopamine-Coated Acellular Mega-Hemoglobin As a Potential Oxygen Therapeutic E Pozy, C Savla, A Palmer 2022 AIChE Annual Meeting, 2022 | | 2022 |
Surface Camouflaged Lumbricus Terrestris mega-Hemoglobin for Diverse Oxygen Therapeutic Applications C Savla, A Palmer 2021 AIChE Annual Meeting, 2021 | | 2021 |
Diverse Oxygen Therapeutic Applications of Surface Camouflaged Extracellular Annelid Mega-Hemoglobin C Savla, A Palmer 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |